Id3 Orchestrates Germinal Center B Cell Development
نویسندگان
چکیده
منابع مشابه
Dynamic changes in Id3 and E-protein activity orchestrate germinal center and plasma cell development
The generation of high-affinity antibodies requires germinal center (GC) development and differentiation of long-lived plasma cells in a multilayered process that is tightly controlled by the activity of multiple transcription factors. Here, we reveal a new layer of complexity by demonstrating that dynamic changes in Id3 and E-protein activity govern both GC and plasma cell differentiation. We ...
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ژورنال
عنوان ژورنال: Molecular and Cellular Biology
سال: 2016
ISSN: 0270-7306,1098-5549
DOI: 10.1128/mcb.00150-16